Galantamine Hydrobromide
(Galanathamine HBr.)
DESCRIPTION:
Galanthamine Hydrobromide is a strong (reversible) cholinesterase inhibitor, increasing the susceptibility of the organism to acetylcholine, and treat for mild to moderate dementia of the Alzheimer's type.
Our galanthamine Hydrobromide is extracted from Lycoris radiata (L.Herit.) Herb), The production facility was inspected and classified as acceptable by U.S FDA in 2006,.To ensure the stable supply of Galanthamine HBr, a large area of herbs have been cultivated and advanced extract technology have been adopted for both enhancing the yield and purifying fine products.
Specifications: 98%
Product Information:
|
CAS Number: |
|
1953-04-4 |
| Origin |
|
Lycoris radiata (LHer.) Herb. |
  |
|
|
Molecular Formula: |
|
C17H21NO3
*HBr |
| Molecular
Weight: |
|
368.27 |
|
Appearance: |
|
White Powder |
| Assay
by HPLC: |
|
98% Min |
Test
Item |
|
Appearance,
Identification, Residue on Ignition, Specific Rotation, Loss on drying, pH, Solvent
Residual, Assay, Ralated Substances |
| Packing: |
|
Nt.W:1kg/aluminum foil bag with inner plastic bag |
|
Storage: |
|
Store in a cool and dry area, keep sealed and keep away from direct light |
Biological effects:
Galanthamine extract is specific,
competitive and reversible acetylcholinesterase
inhibitor. It is also an allosteric modulator
at nicotinic cholinergic receptor sites potentiating
cholinergic nicotinic neurotransmission. Both
the acetylcholine and nicotine receptors have
been suggested as areas related to cognitive impairment.
Initially, Galanthamine extract was used in anesthesiology
to antagonize the effects of non-depolarizing
muscle relaxants, and since then it was rapidly
introduced in other areas of medicine, i.e. neurology,
ophthalmology, gastroenterology, intensive care
and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product
with broad therapeutic index, allowing "soft"
manifestation of its effect with individual dosing
depending on the particular case.
Several trials already showed that
Galantamine 16 and 24 mg/day significantly benefits
the cognitive, functional, and behavioral symptoms
of AD as compared with placebo and proved also
to be very effective in symptomatic treatment
of senile dementia of Alzheimer's type
Relation Links:
1. What is Galantmaine HBr. - http://www.galantamine.cn/galantamine.php
2. What is Lycoris. - http://www.galantamine.cn/lycoris.php
3. What is Alzheimer's disease . - http://www.galantamine.cn/alzheimers.php
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