Herbal Extracts

• Galanthamine Hydrobromide
• (+)-Sodium usnic acid
• (+)-Usnic Acid
• St. John`s wort extract
• Green Tea Extract
• (-)-Epigallocatechin gallate (EGCG)
• (+)-Catechin (C)
• Epicatechin (EC)
• Camptothecin
• Lutein (Oil Suspension)
• Resveratrol
• Gossypol Acetate
• Arctiin & Arctigenin
• Shikimic Acid

 

Published date: Oct 17, 2018   Tags: 1953-04-4 Galanthamine galanthamine hbr Galanthamine Hydrobromide Alzheimer

Galanthamine Hydrobromide is a strong (reversible) cholinesterase inhibitor that increases the susceptibility of an organism to acetylcholine, and is an effective treatment for mild to moderate dementia of the Alzheimer's type.

CAS Number:	1953-04-4
Origin:	Lycoris radiata (LHer.) Herb.
Molecular Structure:
Molecular Formula:	C17H21NO3·HBr
Molecular Weight:	368.27
Appearance:	White Powder
Assay by HPLC:	98% Min
Packing:	1kg/aluminum foil bag with inner plastic bag
Storage:	Store in a cool and dry area, keep sealed and keep away from direct light
GMP Certificate:

Biological effects

Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.

Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.

Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type

Advantages

Natural Product

Yixin Galantamine is isolated from natural herb, non GMO source; it is produced on basis of extraction and purification process, 100% from nature. 

GMP System

Yixin Galantamine facility was inspected and classified as acceptable by US FDA in 2006, 2011, GMP certificate from CFDA has been obtained since 2005, updated 2018.

Cultivation

To ensure the stable supply of Galantamine HBr, a large area of herbs has been cultivated and advanced technology has been adopted to enhance the yield and consistent quality.